HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chlorophenylboronic acid → 5-(2-Chlorophenyl)-1,3-benzodioxole-4-carbaldehyde
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chlorophenylboronic acid | HCID 2734322 | — |
| Reactant | 5-Bromo-1,3-benzodioxole-4-carboxaldehyde | HCID 11031640 | — |
| Product | 5-(2-Chlorophenyl)-1,3-benzodioxole-4-carbaldehyde | HCID 86658679 | — |
Reaction Steps
The process described in Method B was followed. 5-Bromo-1,3-benzodioxole-4-carbaldehyde (0.458 g, 2.00 mmol) and 2-chlorophenylboronic acid (0.469 g, 3.00 mmol) were used to obtain the title compound. The crude product was purified by column chromatography with a mixture of hexane:ethyl acetate (4:1) as the eluent.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08536210B2 |
| Source dataset | uspto-grants-2013_09 |
| ORD ID | ord-3d3e53852d64491a89b5ad87c0035bfe |
| Source note | uspto-grants-2013_09 |