反应详情

Thionyl chloride (5 ml.) and 2.0 g. of 1-[2-(2-naphthyl)-2-hydroxyethyl]imidazole are stirred at room temperature for about 20 minutes. Thereafter, the solution is evaporated to dryness and the residue is treated with ethyl acetate and filtered to yield 1-[2-(2-naphthyl)-2-chloroethyl]imidazole hydrochloride as a white solid.

1. customThereafter, the solution is evaporated to dryness
2. additionthe residue is treated with ethyl acetate
3. filtrationfiltered