Thionyl Chloride → HCID 12698974, compound

HRID 426946Notes

Reaction equation

HRID 426946 reaction equation
S(Cl)([Cl:3])=O.[CH:5]1[C:14]2[C:9](=[CH:10][CH:11]=[CH:12][CH:13]=2)[CH:8]=[CH:7][C:6]=1[CH:15](O)[CH2:16][N:17]1[CH:21]=[CH:20][N:19]=[CH:18]1>>[ClH:3].[CH:5]1[C:14]2[C:9](=[CH:10][CH:11]=[CH:12][CH:13]=2)[CH:8]=[CH:7][C:6]=1[CH:15]([Cl:3])[CH2:16][N:17]1[CH:21]=[CH:20][N:19]=[CH:18]1

Participants

3

Reactant 2

HCID 24386Thionyl ChlorideHCID 130368alpha-2-Naphthalenyl-1H-imidazole-1-ethanol

Product 1

HCID 12698974HCID 12698974, compound

Procedure

Thionyl chloride (5 ml.) and 2.0 g. of 1-[2-(2-naphthyl)-2-hydroxyethyl]imidazole are stirred at room temperature for about 20 minutes. Thereafter, the solution is evaporated to dryness and the residue is treated with ethyl acetate and filtered to yield 1-[2-(2-naphthyl)-2-chloroethyl]imidazole hydrochloride as a white solid.

Workup

  1. customThereafter, the solution is evaporated to dryness
  2. additionthe residue is treated with ethyl acetate
  3. filtrationfiltered

Sources & evidence

ORD record
ord-735fb95fbea24b1dbb8ea17c093b5b87
Source dataset
uspto-grants-1979_10
Patent number
US04172141

Reaction notes

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