Thionyl Chloride → HCID 20389107, compound

HRID 426947Notes

Reaction equation

HRID 426947 reaction equation
[C:1]1([CH:11](O)[CH2:12][N:13]2[CH:17]=[CH:16][N:15]=[CH:14]2)[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][CH:2]=1.S(Cl)([Cl:21])=O>>[ClH:21].[C:1]1([CH:11]([Cl:21])[CH2:12][N:13]2[CH:17]=[CH:16][N:15]=[CH:14]2)[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][CH:2]=1

Participants

3

Reactant 2

HCID 24386Thionyl ChlorideHCID 30542332-(1H-Imidazol-1-yl)-1-(naphthalen-1-yl)ethan-1-ol

Product 1

HCID 20389107HCID 20389107, compound

Procedure

1-[2-(1-naphthyl)-2-hydroxyethyl]imidazole (2.0 g.) and 5 ml. of thionyl chloride are stirred at room temperature for 30 minutes. Thereafter, the reaction mixture is evaporated to dryness and the residue treated with ethyl acetate and filtered to yield 1-[2-(1-naphthyl)-2-chloroethyl]imidazole hydrochloride as a white solid.

Workup

  1. customThereafter, the reaction mixture is evaporated to dryness
  2. additionthe residue treated with ethyl acetate
  3. filtrationfiltered

Sources & evidence

ORD record
ord-3277589f34dc44b3b242bf219bdc05a0
Source dataset
uspto-grants-1979_10
Patent number
US04172141

Reaction notes

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