Trichloroisocyanuric Acid → HCID 70546293, compound

HRID 426988Notes

Reaction equation

HRID 426988 reaction equation
O.O.[O:3]=[C:4]1[CH:9]=[C:8]([CH3:10])[NH:7][CH:6]=[C:5]1[O:11][CH2:12][C:13]([OH:15])=[O:14].[Cl:16]N1C(=[O:23])N(Cl)C(=O)N(Cl)C1=O>CO.O>[OH2:3].[OH2:23].[O:3]=[C:4]1[C:9]([Cl:16])=[C:8]([CH3:10])[NH:7][CH:6]=[C:5]1[O:11][CH2:12][C:13]([OH:15])=[O:14]

Participants

5

Reactant 2

HCID 6909Trichloroisocyanuric AcidHCID 70547366HCID 70547366, compound

Product 1

HCID 70546293HCID 70546293, compound

Reagents, catalysts & solvents 2

HCID 887MethanolSolventHCID 962WaterSolvent2×

Procedure

2-(4-oxo-6-methyl-1,4-dihydropyridin-3-yloxy)acetic acid dihydrate (2.2 g) was dissolved in a mixture of methanol (120 ml) and water (170 ml) under heating on a water bath. The solution was stirred at 65° to 70° C. and trichloroisocyanuric acid (1.1 g) was added thereto. The resultant mixture was stirred for 65° to 70° C. for 1.5 hours. The reaction mixture was left to cool to room temperature with removal of the water bath and filtered. The obtained precipitates were washed with water and dried. The resultant crystals (2.0 g) were dried at 100° C. for 6 hours in vacuo over phosphorus pentoxide to give crystals of 2-(4-oxo-5-chloro-6-methyl-1,4-dihydropyridin-3-yloxy)acetic acid dihydrate, mp 240° to 242° C.

Workup

  1. temperatureunder heating on a water bath
  2. waitThe reaction mixture was left
  3. filtrationfiltered
  4. customThe obtained precipitates
  5. washwere washed with water
  6. customdried
  7. dry with materialThe resultant crystals (2.0 g) were dried at 100° C. for 6 hours in vacuo over phosphorus pentoxide

Sources & evidence

ORD record
ord-77808448cf2f440c8ed6db6cbc3305b9
Source dataset
uspto-grants-1979_10
Patent number
US04172198

Reaction notes

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