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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 427028Generated: October 25, 2026

1-Chloro-2-fluoro-3-nitrobenzene → Ethyl 2-(2-chloro-6-nitroanilino)-5-ethyl-thiophene-3-carboxylate

https://huagongshe.com/reaction/427028

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Chloro-2-fluoro-3-nitrobenzeneHCID 75016—
ReactantEthyl 2-amino-5-ethyl-3-thenoateHCID 78263—
SolventEthanolHCID 702—
ProductEthyl 2-(2-chloro-6-nitroanilino)-5-ethyl-thiophene-3-carboxylateHCID 20387682—

Reaction Steps

Ethyl 2-amino-5-ethyl-thiophene-3-carboxylate and 3-chloro-2-fluoronitrobenzene, m.p. 67°-70° C. (EtOH).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04172831
Source datasetuspto-grants-1979_10
ORD IDord-cdbd6dbddb8f4136a2d630e4a039e40d
Source noteuspto-grants-1979_10