Ethyl 2-amino-5-ethyl-3-thenoate → Ethyl 5-ethyl-2-(2-trifluoromethyl-6-nitroanilino)-thiophene-3-carboxylate

HRID 427029Notes

Reaction equation

HRID 427029 reaction equation
[NH2:1][C:2]1[S:3][C:4]([CH2:12][CH3:13])=[CH:5][C:6]=1[C:7]([O:9][CH2:10][CH3:11])=[O:8].F[C:15]1[C:20]([C:21]([F:24])([F:23])[F:22])=[CH:19][CH:18]=[CH:17][C:16]=1[N+:25]([O-:27])=[O:26]>CCO>[CH2:12]([C:4]1[S:3][C:2]([NH:1][C:15]2[C:16]([N+:25]([O-:27])=[O:26])=[CH:17][CH:18]=[CH:19][C:20]=2[C:21]([F:22])([F:24])[F:23])=[C:6]([C:7]([O:9][CH2:10][CH3:11])=[O:8])[CH:5]=1)[CH3:13]

Participants

4

Reactant 2

HCID 78263Ethyl 2-amino-5-ethyl-3-thenoateHCID 233406452-Fluoro-3-nitrobenzotrifluoride

Product 1

HCID 20387731Ethyl 5-ethyl-2-(2-trifluoromethyl-6-nitroanilino)-thiophene-3-carboxylate

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Ethyl 2-amino-5-ethylthiophene-3-carboxylate and 2-fluoro-3-trifluoromethylnitrobenzene, m.p. 72°-73° C. (EtOH).

Sources & evidence

ORD record
ord-4c089cef134d41669f1b46f92d5e21b1
Source dataset
uspto-grants-1979_10
Patent number
US04172831

Reaction notes

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