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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 427033Generated: October 25, 2026

2,5-Difluoronitrobenzene → Methyl 2-(4-fluoro-2-nitroanilino)-5-phenyl-thiophene-3-carboxylate

https://huagongshe.com/reaction/427033

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,5-DifluoronitrobenzeneHCID 67767—
ReactantMethyl 2-amino-5-phenylthiophene-3-carboxylateHCID 705256—
SolventDichloromethaneHCID 6344—
ProductMethyl 2-(4-fluoro-2-nitroanilino)-5-phenyl-thiophene-3-carboxylateHCID 20387675—

Reaction Steps

Methyl 2-amino-5-phenyl-thiophene-3-carboxylate and 2,5-difluoronitrobenzene, m.p. 150° C. (CH2Cl2).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04172831
Source datasetuspto-grants-1979_10
ORD IDord-918f49a5fc4248348d986b175fdd748a
Source noteuspto-grants-1979_10