HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Ethyl-2-(2-nitroanilino)thiophene-3-carboxylic acid → 2-(2-Aminoanilino)-5-ethylthiophene-3-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Ethyl-2-(2-nitroanilino)thiophene-3-carboxylic acid | HCID 12438960 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 2-(2-Aminoanilino)-5-ethylthiophene-3-carboxylic acid | HCID 12438961 | — |
Reaction Steps
5-Ethyl-2-(2-nitroanilino)-thiophene-3-carboxylic acid (8.0 g, 0.027 mol) in ethanol (150 ml) was catalytically reduced over 10% palladium on charcoal (900 mg) at 60 p.s.i. The catalyst was removed by filtration and the solvent removed by distillation in vacuo to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04172831 |
| Source dataset | uspto-grants-1979_10 |
| ORD ID | ord-788be2a88e484f248f652bffeeae3bf5 |
| Source note | uspto-grants-1979_10 |