Hydrogen Bromide → HCID 13676787, compound

Participants

Reaction Steps

4-Methoxy-10,11-dihydro-5-oxo-5H-dibenzo[a,d]cyclohepten-2-yl acetic acid (0.3 g) is refluxed in acetic acid (4.5 ml) and 48% aqueous hydrobromic acid (4.5 ml) for 30 minutes. The cooled solution is poured into water and extracted with ethyl acetate. The extract is washed, dried, evaporated and the residue recrystallized from ethyl acetate/hexane to afford 4-hydroxy-10,11-dihydro-5-oxo-5H-dibenzo[a,d]cyclohepten-2-yl acetic acid, mp 149°-151°.

Provenance & Evidence