HCID 12361826, compound → HCID 23470202, compound

HRID 427170Notes

Reaction equation

HRID 427170 reaction equation
C[N:2]([CH:11]1[CH2:23][C:22]2[C:21]3[C:16](=[C:17]([F:25])[CH:18]=[C:19](F)[CH:20]=3)[NH:15][C:14]=2[CH2:13][CH2:12]1)[C:3](=O)[C:4]1C=CC=CC=1.C(NC1CC2C3C(=C(F)C=CC=3)NC=2CC1)(=O)C>>[CH2:3]([NH:2][CH:11]1[CH2:23][C:22]2[C:21]3[C:16](=[C:17]([F:25])[CH:18]=[CH:19][CH:20]=3)[NH:15][C:14]=2[CH2:13][CH2:12]1)[CH3:4]

Participants

3

Reactant 2

HCID 12361826HCID 12361826, compoundHCID 12891806HCID 12891806, compound

Product 1

HCID 23470202HCID 23470202, compound

Procedure

Following a reductive procedure similar to that described in Example 260 but substituting for 3-(N-methyl-benzamido)-6,8-difluoro-1,2,3,4-tetrahydrocarbazole an equivalent amount of 3-acetamido-8-fluoro-1,2,3,4-tetrahydrocarbazole there can be obtained 3-(ethylamino)-8-fluoro-1,2,3,4-tetrahydrocarbazole.

Sources & evidence

ORD record
ord-eea461b3dbb6452080cfcb61f833b4e8
Source dataset
uspto-grants-1979_10
Patent number
US04172834

Reaction notes

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