反应详情

A solution of 3-benzyloxyphenylhydrazine hydrochloride (140 g.) and 4-dimethylaminocyclohexanone hydrochloride (100 g.) in 3 liters of ethyl alochol was refluxed for six hours and evaporated to dryness. The solid was suspended in 1 liter of water and filtered to give 119 g. of 3-(dimethylamino)-7-(benzyloxy)-1,2,3,4-tetrahydrocarbazole hydrochloride (Example 239). The water filtrate deposited a solid which was recrystallized from ethyl alcohol to give 38 g. of 3-(dimethylamino)-5-(benzyloxy)-1,2,3,4,-tetrahydrocarbazole hydrochloride, m.p. 207°-209° C.

1. customevaporated to dryness
2. filtrationfiltered
3. customto give 119 g
4. customwas recrystallized from ethyl alcohol
5. customto give 38 g