HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-(4-Phthalimidobut-1-yn-1-yl)-2'-deoxvuridine → 5-(4-Phthalimidobut-1-yl)-2'-deoxyuridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-(4-Phthalimidobut-1-yn-1-yl)-2'-deoxvuridine | HCID 54351651 | — |
| Catalyst | Nickel | HCID 935 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 5-(4-Phthalimidobut-1-yl)-2'-deoxyuridine | HCID 54307558 | 97% |
Reaction Steps
1.00 Gram of 5-(4-Phthalimidobut-1-yn-1-yl)-2′-deoxyuridine was dissolved in 95% EtOH and about 3 g of neutral Raney nickel was added. After 48 hours, the catalyst was removed by cautious filtration and the filtrate was evaporated to a solid which was recrystallized from methanol-water to give 960 mg (97%) of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06312953B1 |
| Source dataset | uspto-grants-2001_11 |
| ORD ID | ord-f678ff06cd824fd3983755b8ca1a4906 |
| Source note | uspto-grants-2001_11 |