HuagongsheHuagongshe Chemistry Print Report · For research reference only
4'-Fluoroacetophenone → 1-(4-Acetylphenyl)-4-(4-pyridyl)piperazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4'-Fluoroacetophenone | HCID 9828 | — |
| Reactant | 4-Fluorobenzophenone | HCID 67663 | — |
| Reactant | 1-(4-Cinnamoylphenyl)-4-(4-pyridyl)piperazine | HCID 53679170 | — |
| Product | 1-(4-Acetylphenyl)-4-(4-pyridyl)piperazine | HCID 18357135 | 40% |
Reaction Steps
The 1-(4-acetylphenyl)-4-(4-pyridyl)piperazine used as starting material was prepared as in Example 32, using 4-fluoroacetophenone as starting material in place of 4-fluorobenzophenone to give 1-(4-acetylphenyl)-4-(4-pyridyl)piperazine (40% yield), m.p. 176-177° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06313127B1 |
| Source dataset | uspto-grants-2001_11 |
| ORD ID | ord-56cc5e7890734fd8bc4174e1de91c4cf |
| Source note | uspto-grants-2001_11 |