4-(Dimethylsulfamoyl)benzoic acid → N1-(4-Methoxybenzoyl)-N2-[4-(dimethylaminosulfonyl)benzoyl]-1,2-benzenediamine

HRID 427586Notes

Reaction equation

HRID 427586 reaction equation
[CH3:1][O:2][C:3]1[CH:18]=[CH:17][C:6]([C:7]([NH:9][C:10]2[C:11]([NH2:16])=[CH:12][CH:13]=[CH:14][CH:15]=2)=[O:8])=[CH:5][CH:4]=1.[CH3:19][N:20]([CH3:33])[S:21]([C:24]1[CH:32]=[CH:31][C:27]([C:28](O)=[O:29])=[CH:26][CH:25]=1)(=[O:23])=[O:22]>>[CH3:1][O:2][C:3]1[CH:4]=[CH:5][C:6]([C:7]([NH:9][C:10]2[C:11]([NH:16][C:28](=[O:29])[C:27]3[CH:31]=[CH:32][C:24]([S:21]([N:20]([CH3:19])[CH3:33])(=[O:23])=[O:22])=[CH:25][CH:26]=3)=[CH:12][CH:13]=[CH:14][CH:15]=2)=[O:8])=[CH:17][CH:18]=1

Participants

3

Reactant 2

HCID 145724-(Dimethylsulfamoyl)benzoic acidHCID 785232N-(2-Aminophenyl)-4-methoxybenzamide

Product 1

HCID 10789847N1-(4-Methoxybenzoyl)-N2-[4-(dimethylaminosulfonyl)benzoyl]-1,2-benzenediamineYield 35%

Procedure

Using the procedure described in Example 55, Part B, N1-(4-methoxybenzoyl)-1,2-benzenediamine (534 mg, 2.21 mmol) was reacted with 4-(dimethylaminosulfonyl)benzoic acid (534 mg, 2.33 mmol) to yield 349 mg (35%) of the title compound.

Sources & evidence

ORD record
ord-38782e7ea8bf478e8ddec462689827ed
Source dataset
uspto-grants-2001_11
Patent number
US06313122B1

Reaction notes

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