4-tert-Butylbenzoyl chloride → HCID 18174536, compound

HRID 427606Notes

Reaction equation

HRID 427606 reaction equation
[C:1]([C:5]1[CH:13]=[CH:12][C:8]([C:9](Cl)=[O:10])=[CH:7][CH:6]=1)([CH3:4])([CH3:3])[CH3:2].[C:14]1(=[O:40])[N:18]([C:19]2[N:24]=[C:23]([NH:25][C:26](=[O:34])[C:27]3[CH:32]=[CH:31][CH:30]=[CH:29][C:28]=3[NH2:33])[CH:22]=[CH:21][CH:20]=2)[C:17](=[O:35])[C:16]2=[CH:36][CH:37]=[CH:38][CH:39]=[C:15]12>>[C:17]1(=[O:35])[N:18]([C:19]2[N:24]=[C:23]([NH:25][C:26](=[O:34])[C:27]3[CH:32]=[CH:31][CH:30]=[CH:29][C:28]=3[NH:33][C:9](=[O:10])[C:8]3[CH:12]=[CH:13][C:5]([C:1]([CH3:4])([CH3:3])[CH3:2])=[CH:6][CH:7]=3)[CH:22]=[CH:21][CH:20]=2)[C:14](=[O:40])[C:15]2=[CH:39][CH:38]=[CH:37][CH:36]=[C:16]12

Participants

3

Reactant 2

HCID 743724-tert-Butylbenzoyl chlorideHCID 18174456HCID 18174456, compound

Product 1

HCID 18174536HCID 18174536, compoundYield 123.1%

Procedure

Using the procedure described in Example 93, Part A, 4-tert-butylbenzoyl chloride (0.47 mmol) and N-(6-phthalimidopyridin-2-yl)-2-aminobenzamide (0.47 mmol) yielded 300 mg (100%) of the title product.

Sources & evidence

ORD record
ord-611ab0fdba5f4ffc9919d91e31d8005a
Source dataset
uspto-grants-2001_11
Patent number
US06313122B1

Reaction notes

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