4-tert-Butylbenzoyl chloride → HCID 18174489, compound

HRID 427613Notes

Reaction equation

HRID 427613 reaction equation
[C:1]([C:5]1[CH:13]=[CH:12][C:8]([C:9](Cl)=[O:10])=[CH:7][CH:6]=1)([CH3:4])([CH3:3])[CH3:2].[NH2:14][C:15]1[CH:31]=[CH:30][C:29]([CH3:32])=[CH:28][C:16]=1[C:17]([NH:19][C:20]1[CH:25]=[CH:24][C:23]([O:26][CH3:27])=[CH:22][CH:21]=1)=[O:18]>>[C:1]([C:5]1[CH:13]=[CH:12][C:8]([C:9]([NH:14][C:15]2[CH:31]=[CH:30][C:29]([CH3:32])=[CH:28][C:16]=2[C:17]([NH:19][C:20]2[CH:21]=[CH:22][C:23]([O:26][CH3:27])=[CH:24][CH:25]=2)=[O:18])=[O:10])=[CH:7][CH:6]=1)([CH3:4])([CH3:3])[CH3:2]

Participants

3

Reactant 2

HCID 743724-tert-Butylbenzoyl chlorideHCID 12233740HCID 12233740, compound

Product 1

HCID 18174489HCID 18174489, compoundYield 47%

Procedure

Using the procedure described in Example 93, Part A, 4-tert-butylbenzoyl chloride (1.3 mmol) and 2-amino-N-(4-methoxyphenyl)-5-methylbenzamide (1.2 mmol) yielded 0.23 g (47%) of the title compound.

Sources & evidence

ORD record
ord-011feaac83d44716bbb2c7301349cedc
Source dataset
uspto-grants-2001_11
Patent number
US06313122B1

Reaction notes

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