4-tert-Butylbenzoyl chloride → HCID 18174627, compound

HRID 427614Notes

Reaction equation

HRID 427614 reaction equation
[C:1]([C:5]1[CH:13]=[CH:12][C:8]([C:9](Cl)=[O:10])=[CH:7][CH:6]=1)([CH3:4])([CH3:3])[CH3:2].[NH2:14][C:15]1[C:31]([CH3:32])=[CH:30][CH:29]=[CH:28][C:16]=1[C:17]([NH:19][C:20]1[CH:25]=[CH:24][C:23]([O:26][CH3:27])=[CH:22][CH:21]=1)=[O:18]>>[C:1]([C:5]1[CH:13]=[CH:12][C:8]([C:9]([NH:14][C:15]2[C:31]([CH3:32])=[CH:30][CH:29]=[CH:28][C:16]=2[C:17]([NH:19][C:20]2[CH:25]=[CH:24][C:23]([O:26][CH3:27])=[CH:22][CH:21]=2)=[O:18])=[O:10])=[CH:7][CH:6]=1)([CH3:4])([CH3:3])[CH3:2]

Participants

3

Reactant 2

HCID 743724-tert-Butylbenzoyl chlorideHCID 16791161HCID 16791161, compound

Product 1

HCID 18174627HCID 18174627, compoundYield 45%

Procedure

Using the procedure described in Example 93, Part A, 4-tert-butylbenzoyl chloride (1.76 mmol) and 2-amino-N-(4-methoxyphenyl)-3-methylbenzamide (1.6 mmol) yielded 0.30 g (45%) of the title compound.

Sources & evidence

ORD record
ord-9e02a9ea0d464acfac5e4302061b8f12
Source dataset
uspto-grants-2001_11
Patent number
US06313122B1

Reaction notes

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