4-tert-Butylbenzoyl chloride → HCID 18174582, compound

HRID 427634Notes

Reaction equation

HRID 427634 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([NH:9][C:10](=[O:21])[C:11]2[C:16]([CH3:17])=[CH:15][CH:14]=[CH:13][C:12]=2[N+:18]([O-])=O)=[CH:5][CH:4]=1.[C:22]([C:26]1[CH:34]=[CH:33][C:29]([C:30](Cl)=[O:31])=[CH:28][CH:27]=1)([CH3:25])([CH3:24])[CH3:23]>>[C:22]([C:26]1[CH:27]=[CH:28][C:29]([C:30]([NH:18][C:12]2[CH:13]=[CH:14][CH:15]=[C:16]([CH3:17])[C:11]=2[C:10]([NH:9][C:6]2[CH:7]=[CH:8][C:3]([O:2][CH3:1])=[CH:4][CH:5]=2)=[O:21])=[O:31])=[CH:33][CH:34]=1)([CH3:25])([CH3:23])[CH3:24]

Participants

3

Reactant 2

HCID 743724-tert-Butylbenzoyl chlorideHCID 18174615HCID 18174615, compound

Product 1

HCID 18174582HCID 18174582, compoundYield 17%

Procedure

Using the procedure described in Example 93, Part B, N-(4-methoxyphenyl)-2-nitro-6-methylbenzamide (1.05 mmol) was reduced to the corresponding amine. Using the procedure described in Example 93, Part A, the amine was reacted with 4-tert-butylbenzoyl chloride (1.05 mmol) to yield 72 mg (17%) of the title compound.

Sources & evidence

ORD record
ord-2929f09ac2284c079ad76304c71a5da5
Source dataset
uspto-grants-2001_11
Patent number
US06313122B1

Reaction notes

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