p-Anisoyl chloride → HCID 18174662, compound

HRID 427652Notes

Reaction equation

HRID 427652 reaction equation
[OH:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[NH:8][C:9](=[O:20])[C:10]1[CH:15]=[CH:14][C:13]([C:16]([CH3:19])([CH3:18])[CH3:17])=[CH:12][CH:11]=1.[C:21](Cl)(=[O:30])[C:22]1[CH:27]=[CH:26][C:25]([O:28][CH3:29])=[CH:24][CH:23]=1>>[CH3:29][O:28][C:25]1[CH:26]=[CH:27][C:22]([C:21]([O:1][C:2]2[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=2[NH:8][C:9](=[O:20])[C:10]2[CH:15]=[CH:14][C:13]([C:16]([CH3:17])([CH3:19])[CH3:18])=[CH:12][CH:11]=2)=[O:30])=[CH:23][CH:24]=1

Participants

3

Reactant 2

HCID 7477p-Anisoyl chlorideHCID 835954HCID 835954, compound

Product 1

HCID 18174662HCID 18174662, compoundYield 61%

Procedure

Using the procedure described in Example 149, Part B, N-(2-hydroxyphenyl)-4-tert-butylbenzamide (2.00 mmol) was reacted with p-anisoyl chloride to yield 494 mg (61%) of the title compound as a crystalline solid.

Sources & evidence

ORD record
ord-a564d2d02a464e07aea7f99b332ebe7e
Source dataset
uspto-grants-2001_11
Patent number
US06313122B1

Reaction notes

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