Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 427698Generated: October 29, 2026

4-(Dimethylamino)benzoic acid → 4-(Dimethylamino)benzoyl chloride

https://huagongshe.com/reaction/427698

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(Dimethylamino)benzoic acidHCID 12092—
ReactantThionyl ChlorideHCID 24386—
SolventDichloromethaneHCID 6344—
Product4-(Dimethylamino)benzoyl chlorideHCID 4400782—

Reaction Steps

A solution of 4-(dimethylamino)benzoic acid and thionyl chloride in methylene chloride was refluxed 4 h. Volatile solvents were removed in vacuo to yield 1.10 g of 4-(dimethylamino)benzoyl chloride. This material was used in subsequent reactions without purification.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06313122B1
Source datasetuspto-grants-2001_11
ORD IDord-238ade33ff684a6788104a4f5129ce03
Source noteuspto-grants-2001_11