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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 428103Generated: October 29, 2026

2-(3-Methyl-1,2-oxazol-5-yl)acetic acid → N-[(3-methylisoxazol-5yl)acetyl]alanine Iso-butyl Ester

https://huagongshe.com/reaction/428103

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(3-Methyl-1,2-oxazol-5-yl)acetic acidHCID 4195532—
Reactant2-methylpropyl (2S)-2-aminopropanoateHCID 13743556—
ProductN-[(3-methylisoxazol-5yl)acetyl]alanine Iso-butyl EsterHCID 15481782—

Reaction Steps

Following General Procedure I above, and using (3-methyl-isoxazol-5-yl)acetic acid (CAS# 19668-85-0) and alanine iso-butyl ester (prepared following General Procedure J above), the title compound was prepared. The reaction was monitored by tlc on silica gel and purification was by filtration as described in the general procedure.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06313152B1
Source datasetuspto-grants-2001_11
ORD IDord-9c05ff008b0d419fb3d69146e03c0a86
Source noteuspto-grants-2001_11