HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(Dimethylamino)ethanol → N-[(3-chlorophenyl)acetyl]alanine 2(N,N-dimethylamino)ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(Dimethylamino)ethanol | HCID 7902 | — |
| Reactant | N-(3-chlorophenylacetyl)alanine | HCID 15481783 | — |
| Product | N-[(3-chlorophenyl)acetyl]alanine 2(N,N-dimethylamino)ethyl ester | HCID 54311846 | — |
Reaction Steps
Following General Procedure C above, and using N-(3-chlorophenyl-acetyl)alanine (from Example D above) and 2-(N,N-dimethyl amino) ethanol (Aldrich), the title compound can be prepared. The reaction was monitored by tlc on silica gel and purification was by liquid chromatography using 0.1:2:0.79 NH4OH:EtOH:CHCl3 as the eluant.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06313152B1 |
| Source dataset | uspto-grants-2001_11 |
| ORD ID | ord-39e590847ceb4dc780a0ad10ab755fbe |
| Source note | uspto-grants-2001_11 |