3-Methoxyphenethylamine → HCID 59972995, compound

HRID 428130Notes

Reaction equation

Cl.[C:2]1(/[C:8](/[C:13]2[CH:14]=[N:15][CH:16]=[CH:17][CH:18]=2)=[CH:9]/[C:10]([OH:12])=O)[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH3:19][O:20][C:21]1[CH:22]=[C:23]([CH:27]=[CH:28][CH:29]=1)[CH2:24][CH2:25][NH2:26]>>[CH3:19][O:20][C:21]1[CH:22]=[C:23]([CH:27]=[CH:28][CH:29]=1)[CH2:24][CH2:25][NH:26][C:10](=[O:12])/[CH:9]=[C:8](/[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1)\[C:13]1[CH:14]=[N:15][CH:16]=[CH:17][CH:18]=1

Participants

Reactant 2

HCID 748663-Methoxyphenethylamine

HCID 69689274HCID 69689274, compound

Product 1

HCID 59972995HCID 59972995, compoundYield 98%

Procedure

Starting from (Z)-3-phenyl-3-(3-pyridyl)-2-propenoic acid hydrochloride (1.00 g) and 3-methoxyphenethylamine (0.60 g), the titled compound (1.33 g, 98%) was obtained according to the method similar to that of Example 9.

Sources & evidence

ORD record: ord-d88b656b0f8244dc8440614803038bbc
Source dataset: uspto-grants-2001_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06313153B1

Reaction notes

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