HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Iodobenzoic acid → 4-[3-(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthyl)-1-propynyl]benzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Iodobenzoic acid | HCID 12085 | — |
| Reactant | 3-(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthyl)-1-propyne | HCID 17773869 | — |
| Product | 4-[3-(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthyl)-1-propynyl]benzoic acid | HCID 15389069 | — |
Reaction Steps
In a similar manner to Example 16(c), by reaction of 8 g (35.3 mmol) of 3-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthyl)-1-propyne with 8 g (32.1 mmol) of 4-iodobenzoic acid, 10.4 g (94%) of the expected acid are obtained, with a melting point of 167-8° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06313162B1 |
| Source dataset | uspto-grants-2001_11 |
| ORD ID | ord-4b04a6c4723742809e881de0ef033e21 |
| Source note | uspto-grants-2001_11 |