反应详情

To a solution of 4-(2-aminophenylamino)benzophenone (Compound 101, 0.58 g, 2 mmol) in toluene (10 ml) was added phenylisocyanate (0.22 ml, 2 mmol). The reaction mixture was heated for 20 hours on a steam bath. After cooling the reaction mixture to room temperature the resulting precipitate was collected by filtration and washed with toluene. The crude product was dissolved in hot isopropanol and crystallized on the addition of water to afford the title compound.

1. temperatureThe reaction mixture was heated for 20 hours on a steam bath
2. filtrationwas collected by filtration
3. washwashed with toluene
4. dissolutionThe crude product was dissolved in hot isopropanol
5. customcrystallized on the addition of water