Acetic Anhydride → N-(2-(4-Benzoylphenylamino)phenyl)acetamide

HRID 428294Notes

Reaction equation

HRID 428294 reaction equation
[NH2:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[NH:8][C:9]1[CH:22]=[CH:21][C:12]([C:13]([C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=2)=[O:14])=[CH:11][CH:10]=1.[C:23](OC(=O)C)(=[O:25])[CH3:24]>>[C:13]([C:12]1[CH:21]=[CH:22][C:9]([NH:8][C:3]2[CH:4]=[CH:5][CH:6]=[CH:7][C:2]=2[NH:1][C:23](=[O:25])[CH3:24])=[CH:10][CH:11]=1)(=[O:14])[C:15]1[CH:16]=[CH:17][CH:18]=[CH:19][CH:20]=1

Participants

3

Reactant 2

HCID 7918Acetic AnhydrideHCID 11737779{4-[(2-Aminophenyl)amino]phenyl}(Phenyl)methanone2×

Product 1

HCID 18358189N-(2-(4-Benzoylphenylamino)phenyl)acetamide

Procedure

4-(2-Aminophenylamino)benzophenone (Compound 101, 0.58 g, 2 mmol) was dissolved in acetic anhydride (10 ml) and the solution was stirred at room temperature for 3 hours. The precipitate that forms after 75 min was filtered off and washed with water to afford the title compound.

Workup

  1. waitThe precipitate that forms after 75 min
  2. filtrationwas filtered off
  3. washwashed with water

Sources & evidence

ORD record
ord-3626457397764f5681709ebfb618c5cb
Source dataset
uspto-grants-2001_11
Patent number
US06313174B1

Reaction notes

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