Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3-(1,4-dioxaspiro[4.5]decan-8-yl)-1H-indole → 3-(1,4-Dioxa-spiro[4,5]dec-8-yl)-4-fluoro-1H-indole
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3-(1,4-dioxaspiro[4.5]decan-8-yl)-1H-indole | HCID 10848753 | — |
| 반응물 | 3-(1,4-dioxa-spiro[4,5]dec-7-en-8-yl)-4-fluoro-1H-indole | HCID 18414055 | — |
| 생성물 | 3-(1,4-Dioxa-spiro[4,5]dec-8-yl)-4-fluoro-1H-indole | HCID 18414088 | 70% |
반응 단계
This compound was prepared in the manner described above for intermediate 2a by replacing 3-(1,4-dioxa-spiro[4,5]dec-7-en-8-yl)-1H-indole with 3-(1,4-dioxa-spiro[4,5]dec-7-en-8-yl)-4-fluoro-1H-indole (6.3 g) ) to afford 4.44 g (70%) of the title compound as a white solid: mp 161-162° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06313126B1 |
| 출처 데이터셋 | uspto-grants-2001_11 |
| ORD ID | ord-cd046b07deb44e04bd362ccecd2ba9bc |
| 출처 메모 | uspto-grants-2001_11 |