4-(5-Cyano-1-methyl-3-indolyl)cyclohexanone → 4-(5-Cyano-1-n-propyl-3-indolyl)-cyclohexanone

Participants

Reaction Steps

This compound was prepared in the manner described above for intermediate 6a by replacing 3-(1,4-dioxa-spiro[4,5]dec-8-yl)-5-cyano-1-methyl-indole with 3-(1,4-dioxa-spiro[4,5]-dec-8-yl)-5-cyano-1-n-propyl-indole (2.64 g, 8.2 mmol) to afford 1.67 g (73%) of the title compound as a white solid: mp 103-104° C.; MS EI m/e 280 (M+).

Provenance & Evidence