4-(5-Cyano-1-methyl-3-indolyl)cyclohexanone → 4-(5-Cyano-1-isopropyl-3-indolyl)-cyclohexanone

Participants

Reaction Steps

This compound was prepared in the manner described above for intermediate 6a by replacing 3-(1,4-dioxa-spiro[4,5]dec-8-yl)-5-cyano-1-methyl-indole with 3-(1,4-dioxa-spiro[4,5]-dec-8-yl)-5-cyano-1-isopropyl-indole (5.86 g, 16 mmol) to afford 3.46 g (63%) of the title compound as a white solid: mp 106-107° C.

Provenance & Evidence