HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 4-methylaminobenzoate → Methyl 4-{N-[1-(S)-phenyl-2-(pyrrolidin-1-yl)ethyl]-N-methylamino}benzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 4-methylaminobenzoate | HCID 140375 | — |
| Reactant | 1-(S)-phenyl-2-(pyrrolidin-1-yl)ethanol | HCID 7195213 | — |
| Reactant | (R)-2-Phenyl-2-pyrrolidin-1-yl-ethanol | HCID 11030628 | — |
| Product | Methyl 4-{N-[1-(S)-phenyl-2-(pyrrolidin-1-yl)ethyl]-N-methylamino}benzoate | HCID 69950222 | 52% |
Reaction Steps
This was prepared from the mixture of 2-(R)-phenyl-2-(pyrrolidin-1-yl)ethanol and 1-(S)-phenyl-2-(pyrrolidin-1-yl)ethanol and methyl 4-methylaminobenzoate in 52% yield according to a procedure similar to that described in Example 1 (i).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06313302B2 |
| Source dataset | uspto-grants-2001_11 |
| ORD ID | ord-1b882b7d06eb46a5aa6fbbab842066cb |
| Source note | uspto-grants-2001_11 |