HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 4-aminobenzoate → Methyl 4-{N-[2-(3-(S)-methoxymethoxypyrrolidin-1-yl)-1-(S)-phenylethyl]amino}benzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 4-aminobenzoate | HCID 12082 | — |
| Reactant | 2-(3-(S)-methoxymethoxypyrrolidin-1-yl)-1-(S)-phenyethanol | HCID 15520998 | — |
| Reactant | 2-(3-(S)-methoxymethoxypyrrolidin-1-y)-2-(R)-phenylethanol | HCID 15520999 | — |
| Product | Methyl 4-{N-[2-(3-(S)-methoxymethoxypyrrolidin-1-yl)-1-(S)-phenylethyl]amino}benzoate | HCID 54255710 | 69% |
Reaction Steps
This was prepared from 2-(3-(S)-methoxymethoxypyrrolidin-1-yl)-1-(S)-phenylethanol and 2-(3-(S)-methoxymethoxypyrrolidin-1-yl)-2-(R)-phenylethanol and methyl 4-aminobenzoate in 69% yield according to a procedure similar to that described in Example 1 (i).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06313302B2 |
| Source dataset | uspto-grants-2001_11 |
| ORD ID | ord-aaf1a7e31c9b4275ae0f55db3cdca06e |
| Source note | uspto-grants-2001_11 |