HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 4-methylaminobenzoate → Methyl 4-{n-[2-(3-(s)methoxymethoxypyrrolidin-1-yl)-1(r)-phenylethyl]-n-methylamino}benzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 4-methylaminobenzoate | HCID 140375 | — |
| Reactant | 1-Phenylethanol, (R)- | HCID 637516 | — |
| Reactant | 2-(3-(s)Methoxymethoxypyrrolidin-1-yl)-2-(s)-phenylethanol | HCID 53730535 | — |
| Product | Methyl 4-{n-[2-(3-(s)methoxymethoxypyrrolidin-1-yl)-1(r)-phenylethyl]-n-methylamino}benzoate | HCID 69950347 | 49% |
Reaction Steps
This was prepared from 2-(3S)-methoxymethoxypyrrolidin-1-yl)-1-(R)-phenylethanol and 2-(3-(S)-methoxymethoxypyrrolidin-1-yl)-2-(S)-phenylethanol and methyl 4-methylaminobenzoate in 49% yield according to a procedure similar to that described in Example 1 (i).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06313302B2 |
| Source dataset | uspto-grants-2001_11 |
| ORD ID | ord-698aaac3ba54457094d2ce60cf484a5a |
| Source note | uspto-grants-2001_11 |