HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Methoxy-4-(2-morpholin-4-yl-ethoxy)-benzaldehyde → HCID 15548054, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Methoxy-4-(2-morpholin-4-yl-ethoxy)-benzaldehyde | HCID 874621 | — |
| Reactant | HCID 178462451 | HCID 178462451 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 15548054 | HCID 15548054 | — |
Reaction Steps
3-Hydroxy-3-[3-methoxy-4-[2-(4-morpholinyl)-ethoxy]-phenyl]-1-propyne was prepared according to Method A above from 3-methoxy-4-(2-morpholin-4-yl-ethoxy)-benzaldehyde (0.60 g, 2.26 mmol) (see below) in THF (25 mL) and ethynylmagnesium chloride (5 mmol, 10 mL, 0.5M solution in tetrahydrofuran) (Aldrich). (Yield 502 mg, 76%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06313310B1 |
| Source dataset | uspto-grants-2001_11 |
| ORD ID | ord-5082f990b5fe469997c3344353406bc5 |
| Source note | uspto-grants-2001_11 |