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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 429014Generated: October 28, 2026

HCID 165579, compound → Paromomycin

https://huagongshe.com/reaction/429014

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 165579HCID 165579—
Reactant5-TAMRAHCID 2762602—
SolventDimethylformamideHCID 6228—
SolventSodium BicarbonateHCID 516892—
ProductParomomycinHCID 165580—

Reaction Steps

Paramomycin TAMRA was synthesized by reacting 55 mg paramomycin sulphate in sodium bicarbonate (6 mL 0.067M in 30% dimethyl formamide (DMF) with 5 mg 5-carboxytetramethyl rhodamine (in 1 mL DMF) over 12 hours at room temp. The solution was diluted and purified by anion exchange chromatography, and reversed phase HPLC (Wang et al., 1997).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06316194B1
Source datasetuspto-grants-2001_11
ORD IDord-0619db7ecae64eb199805b39007943a6
Source noteuspto-grants-2001_11