HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 165579, compound → Paromomycin
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 165579 | HCID 165579 | — |
| Reactant | 5-TAMRA | HCID 2762602 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Solvent | Sodium Bicarbonate | HCID 516892 | — |
| Product | Paromomycin | HCID 165580 | — |
Reaction Steps
Paramomycin TAMRA was synthesized by reacting 55 mg paramomycin sulphate in sodium bicarbonate (6 mL 0.067M in 30% dimethyl formamide (DMF) with 5 mg 5-carboxytetramethyl rhodamine (in 1 mL DMF) over 12 hours at room temp. The solution was diluted and purified by anion exchange chromatography, and reversed phase HPLC (Wang et al., 1997).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06316194B1 |
| Source dataset | uspto-grants-2001_11 |
| ORD ID | ord-0619db7ecae64eb199805b39007943a6 |
| Source note | uspto-grants-2001_11 |