5-(m-Tolyl)oxazole-4-carboxylic acid → 5-m-Tolyl-oxazole-4-carboxylic acid [2-(5-acetyl-furan-2-ylmethyl)-2H-[1,2,3]triazol-4-yl]-amide
Reaction equation
[CH3:1][C:2]1([C:7]2[O:11][C:10]([CH2:12][N:13]3[N:17]=[C:16]([NH2:18])[CH:15]=[N:14]3)=[CH:9][CH:8]=2)[O:6]CCO1.[C:19]1([CH3:33])[CH:24]=[CH:23][CH:22]=[C:21]([C:25]2[O:29][CH:28]=[N:27][C:26]=2[C:30](O)=[O:31])[CH:20]=1>>[C:2]([C:7]1[O:11][C:10]([CH2:12][N:13]2[N:17]=[C:16]([NH:18][C:30]([C:26]3[N:27]=[CH:28][O:29][C:25]=3[C:21]3[CH:20]=[C:19]([CH3:33])[CH:24]=[CH:23][CH:22]=3)=[O:31])[CH:15]=[N:14]2)=[CH:9][CH:8]=1)(=[O:6])[CH3:1]Participants
3
Procedure
Following general procedure A followed by L, starting from 2-[5-(2-methyl-[1,3]dioxolan-2-yl)-furan-2-ylmethyl]-2H-[1,2,3]triazol-4-ylamine and 5-(m-tolyl)-oxazole-4-carboxylic acid.
Sources & evidence
- ORD record
- ord-959b4af1c3e346458927abccf54e4d1e
- Source dataset
- uspto-grants-2013_09
- Patent number
- US08536209B2
Reaction notes
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