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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 42905Generated: October 27, 2026

2-Methyl-5-(3-trifluoromethylphenyl)oxazole-4-carboxylic acid → 2-Methyl-5-(3-trifluoromethyl-phenyl)-oxazole-4-carboxylic acid [2-(5-acetyl-furan-2-ylmethyl)-2H-[1,2,3]triazol-4-yl]-amide

https://huagongshe.com/reaction/42905

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Methyl-5-(3-trifluoromethylphenyl)oxazole-4-carboxylic acidHCID 66929116—
Reactant2-[5-(2-Methyl-[1,3]dioxolan-2-yl)-furan-2-ylmethyl]-2H-[1,2,3]triazol-4-ylamineHCID 67364247—
Product2-Methyl-5-(3-trifluoromethyl-phenyl)-oxazole-4-carboxylic acid [2-(5-acetyl-furan-2-ylmethyl)-2H-[1,2,3]triazol-4-yl]-amideHCID 42646030—

Reaction Steps

Following general procedure A followed by L, starting from 2-[5-(2-methyl-[1,3]dioxolan-2-yl)-furan-2-ylmethyl]-2H-[1,2,3]triazol-4-ylamine and 5-(3-trifluoromethyl-phenyl)-2-methyl-oxazole-4-carboxylic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08536209B2
Source datasetuspto-grants-2013_09
ORD IDord-05eb843862014dfb8d54728417779e0f
Source noteuspto-grants-2013_09