HCID 66867836, compound → 2-Methyl-5-(3-trifluoromethoxy-phenyl)-oxazole-4-carboxylic acid [2-(5-acetyl-furan-2-ylmethyl)-2H-[1,2,3]triazol-4-yl]-amide

HRID 42906Notes

Reaction equation

HRID 42906 reaction equation
[CH3:1][C:2]1([C:7]2[O:11][C:10]([CH2:12][N:13]3[N:17]=[C:16]([NH2:18])[CH:15]=[N:14]3)=[CH:9][CH:8]=2)[O:6]CCO1.[F:19][C:20]([F:38])([F:37])[O:21][C:22]1[CH:23]=[C:24]([C:28]2[O:32][C:31]([CH3:33])=[N:30][C:29]=2[C:34](O)=[O:35])[CH:25]=[CH:26][CH:27]=1>>[C:2]([C:7]1[O:11][C:10]([CH2:12][N:13]2[N:17]=[C:16]([NH:18][C:34]([C:29]3[N:30]=[C:31]([CH3:33])[O:32][C:28]=3[C:24]3[CH:25]=[CH:26][CH:27]=[C:22]([O:21][C:20]([F:37])([F:19])[F:38])[CH:23]=3)=[O:35])[CH:15]=[N:14]2)=[CH:9][CH:8]=1)(=[O:6])[CH3:1]

Participants

3

Reactant 2

HCID 66867836HCID 66867836, compoundHCID 673642472-[5-(2-Methyl-[1,3]dioxolan-2-yl)-furan-2-ylmethyl]-2H-[1,2,3]triazol-4-ylamine

Product 1

HCID 426460312-Methyl-5-(3-trifluoromethoxy-phenyl)-oxazole-4-carboxylic acid [2-(5-acetyl-furan-2-ylmethyl)-2H-[1,2,3]triazol-4-yl]-amide

Procedure

Following general procedure A followed by L, starting from 2-[5-(2-methyl-[1,3]dioxolan-2-yl)-furan-2-ylmethyl]-2H-[1,2,3]triazol-4-ylamine and 5-(3-trifluoromethoxy-phenyl)-2-methyl-oxazole-4-carboxylic acid.

Sources & evidence

ORD record
ord-94d6b08486f940708e21a7d0c099229b
Source dataset
uspto-grants-2013_09
Patent number
US08536209B2

Reaction notes

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