1-Chloroethyl chloroformate → HCID 18354589, compound
Reaction equation
[Br:1][C:2]1[CH:3]=[C:4]([NH:8][S:9]([C:12]2[CH:17]=[CH:16][C:15]([O:18][CH3:19])=[C:14]([N:20]3[CH2:25][CH2:24][N:23](C)[CH2:22][CH2:21]3)[CH:13]=2)(=[O:11])=[O:10])[CH:5]=[CH:6][CH:7]=1.ClC(OC(Cl)C)=O>>[Br:1][C:2]1[CH:3]=[C:4]([NH:8][S:9]([C:12]2[CH:17]=[CH:16][C:15]([O:18][CH3:19])=[C:14]([N:20]3[CH2:21][CH2:22][NH:23][CH2:24][CH2:25]3)[CH:13]=2)(=[O:11])=[O:10])[CH:5]=[CH:6][CH:7]=1Participants
3
Procedure
The title compound was prepared using a similar procedure to that of example E29 using N-(3-bromophenyl)-4-methoxy-3-(4-methylpiperazin-1-yl)benzenesulfonamide (E3) and 1-chloroethyl chloroformate.
Sources & evidence
- ORD record
- ord-27f2722e85ce4eadb491b80399d587a9
- Source dataset
- uspto-grants-2001_11
- Patent number
- US06316450B1
Reaction notes
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