反应详情

To p-azidotoluene (2.2 mM) prepared as above was added N-bromosuccinimide (2.48 mM), and azo-isobutyronitrile (0.214 mM) in anhydrous benzene (5 ml). This was left to reflux for 5 hours, with the reaction being monitored by TLC. The organics were extracted into diethyl ether (3×15 ml), and water, dried over magnesium sulphate, and the excess solvent removed under vacuum. The p-azidobenzyl bromide formed was isolated using chromatographic techniques.

1. waitThis was left
2. temperatureto reflux for 5 hours, with the reaction
3. extractionThe organics were extracted into diethyl ether (3×15 ml), and water
4. dry with materialdried over magnesium sulphate
5. customthe excess solvent removed under vacuum