Triethylamine → HCID 11312540, compound

Participants

Reaction Conditions

Reaction Steps

To a 0° C. solution of 4-phenoxy benzaldehyde (F) (1.00 g, 5.04 mmol) and trimethylsilyl cyanide (0.63 mL, 5.04 mmol) in dichloromethane (20 mL) was added triethylamine (0.07 mL, 0.5 mmol). The reaction mixture was stirred at 0° C. for 3 h and then concentrated to give (4-phenoxyphenyl)-trimethylsilanyloxy-acetonitrile (G) as a clear oil. This protected cyanohydrin (G) was used without further purification.

Provenance & Evidence