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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 429229Generated: October 29, 2026

Isopropylamine → 3-[(4'-{[(2R,5R)-2,5-dimethylpyrrolidinyl]carbonyl}[1,1'-biphenyl]-4-yl)oxy]-N-isopropyl-1-propanamine

https://huagongshe.com/reaction/429229

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIsopropylamineHCID 6363—
Reactant(2R,5R)-1-{[4'-(3-chloropropoxy)[1,1'-biphenyl]-4-yl]carbonyl}-2,5-dimethylpyrrolidineHCID 70141087—
Product3-[(4'-{[(2R,5R)-2,5-dimethylpyrrolidinyl]carbonyl}[1,1'-biphenyl]-4-yl)oxy]-N-isopropyl-1-propanamineHCID 70140931—

Reaction Steps

The product from Example 4A and isopropylamine were processed as described in Example 10F to provide the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06316475B1
Source datasetuspto-grants-2001_11
ORD IDord-52af5dc946074ec185fe4294a33ce2ac
Source noteuspto-grants-2001_11