HuagongsheHuagongshe Chemistry Print Report · For research reference only
(2R,5R)-2,5-dimethylpyrrolidine hydrochloride → (2R,5R)-1-[(4'-{3-[(2R,5R)-2,5-dimethylpyrrolidinyl]propoxy}[1,1'-biphenyl]-4-yl)carbonyl]-2,5-dimethylpyrrolidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (2R,5R)-2,5-dimethylpyrrolidine hydrochloride | HCID 12268509 | — |
| Reactant | (2R,5R)-1-{[4'-(3-chloropropoxy)[1,1'-biphenyl]-4-yl]carbonyl}-2,5-dimethylpyrrolidine | HCID 70141087 | — |
| Product | (2R,5R)-1-[(4'-{3-[(2R,5R)-2,5-dimethylpyrrolidinyl]propoxy}[1,1'-biphenyl]-4-yl)carbonyl]-2,5-dimethylpyrrolidine | HCID 70140096 | — |
Reaction Steps
The product from Example 4A and (2R,5R)-2,5-dimethylpyrrolidine hydrochloride were processed as described in Example 10F to provide the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06316475B1 |
| Source dataset | uspto-grants-2001_11 |
| ORD ID | ord-b620f2ca8a6b4136baf56bf39dc382a1 |
| Source note | uspto-grants-2001_11 |