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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 429241Generated: October 25, 2026

(R)-(+)-N-Methyl-1-phenylethylamine → N-methyl-N-[(1R)-1-phenylethyl]-N-(3-{[4'-(1-pyrrolidinylcarbonyl)[1,1'-biphenyl]-4-yl]oxy}propyl)amine

https://huagongshe.com/reaction/429241

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(R)-(+)-N-Methyl-1-phenylethylamineHCID 2060888—
Reactant[4'-(3-Chloropropoxy)[1,1'-biphenyl]-4-yl](pyrrolidin-1-yl)methanoneHCID 22994486—
ProductN-methyl-N-[(1R)-1-phenylethyl]-N-(3-{[4'-(1-pyrrolidinylcarbonyl)[1,1'-biphenyl]-4-yl]oxy}propyl)amineHCID 20703894—

Reaction Steps

The product from Example 11A and N-methyl-N-[(1R)-1-phenylethyl]amine were processed as described in Example 10F to provide the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06316475B1
Source datasetuspto-grants-2001_11
ORD IDord-ee784466adc346289945d347bac8281a
Source noteuspto-grants-2001_11