HuagongsheHuagongshe Chemistry Print Report · For research reference only
rel-(2R,6S)-2,6-Dimethylpiperidine → (2R,6S)-2,6-dimethyl-1-(3-{[4'-(1-pyrrolidinylcarbonyl)[1,1'-biphenyl]-4-yl]oxy}propyl)piperidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | rel-(2R,6S)-2,6-Dimethylpiperidine | HCID 641768 | — |
| Reactant | [4'-(3-Chloropropoxy)[1,1'-biphenyl]-4-yl](pyrrolidin-1-yl)methanone | HCID 22994486 | — |
| Product | (2R,6S)-2,6-dimethyl-1-(3-{[4'-(1-pyrrolidinylcarbonyl)[1,1'-biphenyl]-4-yl]oxy}propyl)piperidine | HCID 70141065 | — |
Reaction Steps
The product from Example 11A and (2R,6S)-2,6-dimethylpiperidine were processed as described in Example 10F to provide the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06316475B1 |
| Source dataset | uspto-grants-2001_11 |
| ORD ID | ord-5776e4694b23475da398be011cde973e |
| Source note | uspto-grants-2001_11 |