5-(3-Chloro-phenyl)-2-methyl-oxazole-4-carboxylic acid → HCID 42647240, compound

HRID 42928Notes

Reaction equation

HRID 42928 reaction equation
[CH3:1][C:2]1([C:7]2[S:11][C:10]([CH2:12][N:13]3[N:17]=[C:16]([NH2:18])[CH:15]=[N:14]3)=[CH:9][CH:8]=2)[O:6]CCO1.[Cl:19][C:20]1[CH:21]=[C:22]([C:26]2[O:30][C:29]([CH3:31])=[N:28][C:27]=2[C:32](O)=[O:33])[CH:23]=[CH:24][CH:25]=1>>[C:2]([C:7]1[S:11][C:10]([CH2:12][N:13]2[N:17]=[C:16]([NH:18][C:32]([C:27]3[N:28]=[C:29]([CH3:31])[O:30][C:26]=3[C:22]3[CH:23]=[CH:24][CH:25]=[C:20]([Cl:19])[CH:21]=3)=[O:33])[CH:15]=[N:14]2)=[CH:9][CH:8]=1)(=[O:6])[CH3:1]

Participants

3

Reactant 2

HCID 534307265-(3-Chloro-phenyl)-2-methyl-oxazole-4-carboxylic acidHCID 67365175HCID 67365175, compound

Product 1

HCID 42647240HCID 42647240, compound

Procedure

Following general procedure A followed by B, starting from 2-[5-(2-methyl-[1,3]dioxolan-2-yl)-thiophen-2-ylmethyl]-2H-[1,2,3]triazol-4-ylamine and 5-(3-chloro-phenyl)-2-methyl-oxazole-4-carboxylic acid.

Sources & evidence

ORD record
ord-b6c8b8a5bfd64a59a5a1267906b4bd21
Source dataset
uspto-grants-2013_09
Patent number
US08536209B2

Reaction notes

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