1-Benzyloxycarbonyl-2-(1-aminoethyl)-4-tert-butyloxycarbonylpiperazine → HCID 70123434, compound

HRID 429298Notes

Reaction equation

HRID 429298 reaction equation
CS([C:5]1[N:10]=[C:9]([N:11]2[C:19]3[C:14](=[CH:15][CH:16]=[CH:17][CH:18]=3)[CH:13]=[CH:12]2)[CH:8]=[CH:7][N:6]=1)(=O)=O.[CH2:20]([O:27][C:28]([N:30]1[CH2:35][CH2:34][N:33]([C:36]([O:38][C:39]([CH3:42])([CH3:41])[CH3:40])=[O:37])[CH2:32][CH:31]1[CH:43]([NH2:45])[CH3:44])=[O:29])[C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1>>[CH2:20]([O:27][C:28]([N:30]1[CH2:35][CH2:34][N:33]([C:36]([O:38][C:39]([CH3:40])([CH3:41])[CH3:42])=[O:37])[CH2:32][CH:31]1[CH:43]([NH:45][C:5]1[N:10]=[C:9]([N:11]2[C:19]3[C:14](=[CH:15][CH:16]=[CH:17][CH:18]=3)[CH:13]=[CH:12]2)[CH:8]=[CH:7][N:6]=1)[CH3:44])=[O:29])[C:21]1[CH:22]=[CH:23][CH:24]=[CH:25][CH:26]=1

Participants

3

Reactant 2

HCID 183428831-Benzyloxycarbonyl-2-(1-aminoethyl)-4-tert-butyloxycarbonylpiperazineHCID 18354396HCID 18354396, compound

Product 1

HCID 70123434HCID 70123434, compound

Procedure

The title compound was prepared from 2-methanesulfonyl-4-[indol-1-yl]pyrimidine (125 mg) and 1-benzyloxycarbonyl-2-(1-aminoethyl)-4-tert-butyloxycarbonylpiperazine (EXAMPLE 28; 166 mg) according to the procedure described in EXAMPLE 14, Step E. Mass spectrum (ESI) 557.3 (M+1).

Sources & evidence

ORD record
ord-50186c5ab1c84279a99ac786b4c36aed
Source dataset
uspto-grants-2001_11
Patent number
US06316444B1

Reaction notes

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