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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 42933Generated: October 29, 2026

5-(3-Dimethylamino-phenyl)-oxazole-4-carboxylic acid → 5-(3-Dimethylamino-phenyl)-oxazole-4-carboxylic acid [2-(5-acetyl-thiophen-2-ylmethyl)-2H-[1,2,3]triazol-4-yl]-amide

https://huagongshe.com/reaction/42933

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-(3-Dimethylamino-phenyl)-oxazole-4-carboxylic acidHCID 53211343—
Reactant2-[5-(2-Methyl-[1,3]dioxolan-2-yl)-thiophen-2-ylmethyl]-2H-[1,2,3]triazol-4-ylamineHCID 67365175—
Product5-(3-Dimethylamino-phenyl)-oxazole-4-carboxylic acid [2-(5-acetyl-thiophen-2-ylmethyl)-2H-[1,2,3]triazol-4-yl]-amideHCID 67366452—

Reaction Steps

Following general procedure A followed by B, starting from 2-[5-(2-methyl-[1,3]dioxolan-2-yl)-thiophen-2-ylmethyl]-2H-[1,2,3]triazol-4-ylamine and 5-(3-dimethylamino-phenyl)-oxazole-4-carboxylic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08536209B2
Source datasetuspto-grants-2013_09
ORD IDord-ebe59b7fd406464f8632c16f6b484666
Source noteuspto-grants-2013_09