HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thiophenol → 2-(2-Phenylthioethyl)-1-methylpyrrolidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thiophenol | HCID 7969 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 2-(2-Chloroethyl)-1-methylpyrrolidine | HCID 285093 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 2-(2-Phenylthioethyl)-1-methylpyrrolidine | HCID 10513195 | 10,012.5% |
Reaction Steps
2-(2-Chloroethyl)-1-methylpyrrolidine (1.30 g, 0.08 mmole), thiophenol (1.00 g, 9.08 mmole), potassium carbonate (12.56 g, 90.8 mmole) and DMF (18 mL) were combined, yielding 1.77 g (8.01 mmole, 89%) of the desired compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06316490B1 |
| Source dataset | uspto-grants-2001_11 |
| ORD ID | ord-c4208d7a556d462fb8d775cab8ac8391 |
| Source note | uspto-grants-2001_11 |