HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanimidamide, N,N-diphenyl- → 2-(3-Bromobenzoyl)-3-phenylaminoacrylonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanimidamide, N,N-diphenyl- | HCID 78296 | — |
| Reactant | 3-(3-Bromophenyl)-3-oxopropanenitrile | HCID 2756839 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Solvent | O-Xylene | HCID 7237 | — |
| Product | 2-(3-Bromobenzoyl)-3-phenylaminoacrylonitrile | HCID 69686607 | 74.3% |
Reaction Steps
A mixture of 2-(3-bromobenzoyl)acetonitrile (16.5 g, 73.6 mmol) and N,N-diphenylformamidine (14.5 g, 73.6 mmol) in xylene (100 ml) was heated at reflux under a nitrogen atmosphere. After 3 h, the reaction mixture was cooled to room temperature and diluted with ether to give 2-(3-bromobenzoyl)-3-phenylaminoacrylonitrile (17.9 g) as a solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06316466B1 |
| Source dataset | uspto-grants-2001_11 |
| ORD ID | ord-4e07e7d566e647afa0fd90a248f18e31 |
| Source note | uspto-grants-2001_11 |