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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 42936Generated: October 29, 2026

5-(4-Fluorophenyl)-1,3-oxazole-4-carboxylic acid → 5-(4-Fluoro-phenyl)-oxazole-4-carboxylic acid [2-(5-acetyl-thiophen-2-ylmethyl)-2H-[1,2,3]triazol-4-yl]-amide

https://huagongshe.com/reaction/42936

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-(4-Fluorophenyl)-1,3-oxazole-4-carboxylic acidHCID 52983870—
Reactant2-[5-(2-Methyl-[1,3]dioxolan-2-yl)-thiophen-2-ylmethyl]-2H-[1,2,3]triazol-4-ylamineHCID 67365175—
Product5-(4-Fluoro-phenyl)-oxazole-4-carboxylic acid [2-(5-acetyl-thiophen-2-ylmethyl)-2H-[1,2,3]triazol-4-yl]-amideHCID 42643659—

Reaction Steps

Following general procedure A followed by B, starting from 2-[5-(2-methyl-[1,3]dioxolan-2-yl)-thiophen-2-ylmethyl]-2H-[1,2,3]triazol-4-ylamine and 5-(4-fluoro-phenyl)-oxazole-4-carboxylic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08536209B2
Source datasetuspto-grants-2013_09
ORD IDord-0b1c30abe13b4e6ab9d9b4c6c7fc866f
Source noteuspto-grants-2013_09